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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
USP15
All Species:
18.18
Human Site:
Y580
Identified Species:
50
UniProt:
Q9Y4E8
Number Species:
8
Phosphosite Substitution
Charge Score:
0.25
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y4E8
NP_006304.1
981
112419
Y580
E
K
F
R
H
S
S
Y
T
H
H
T
G
S
S
Chimpanzee
Pan troglodytes
XP_509182
981
112428
Y580
E
K
F
R
H
S
S
Y
T
H
H
T
G
S
S
Rhesus Macaque
Macaca mulatta
XP_001116743
981
112401
Y580
E
K
F
R
H
S
S
Y
T
H
H
T
G
S
S
Dog
Lupus familis
XP_849935
981
112360
Y580
E
K
F
R
H
S
S
Y
T
H
H
T
G
S
S
Cat
Felis silvestris
Mouse
Mus musculus
Q8R5H1
981
112306
Y580
E
K
F
R
H
S
S
Y
T
H
H
T
G
S
S
Rat
Rattus norvegicus
Q6J1Y9
1357
150284
H868
Q
K
T
H
W
P
D
H
K
G
L
C
R
P
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001082452
975
110692
E586
R
D
D
I
F
V
Y
E
V
K
P
R
K
A
E
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q93Y01
910
102631
A521
S
I
R
D
L
I
T
A
L
G
T
A
C
L
L
Baker's Yeast
Sacchar. cerevisiae
P39538
1254
143174
E713
G
G
Y
I
P
F
P
E
P
V
G
N
R
T
D
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.9
100
98.9
N.A.
97.6
26.3
N.A.
N.A.
N.A.
58.2
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
100
100
99.5
N.A.
99.2
41.3
N.A.
N.A.
N.A.
74
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
100
N.A.
100
6.6
N.A.
N.A.
N.A.
0
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
20
N.A.
N.A.
N.A.
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
35.9
24.8
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
56.2
41.9
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
6.6
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
12
0
0
0
12
0
12
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
12
12
0
0
% C
% Asp:
0
12
12
12
0
0
12
0
0
0
0
0
0
0
12
% D
% Glu:
56
0
0
0
0
0
0
23
0
0
0
0
0
0
23
% E
% Phe:
0
0
56
0
12
12
0
0
0
0
0
0
0
0
0
% F
% Gly:
12
12
0
0
0
0
0
0
0
23
12
0
56
0
0
% G
% His:
0
0
0
12
56
0
0
12
0
56
56
0
0
0
0
% H
% Ile:
0
12
0
23
0
12
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
67
0
0
0
0
0
0
12
12
0
0
12
0
0
% K
% Leu:
0
0
0
0
12
0
0
0
12
0
12
0
0
12
12
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
12
0
0
0
% N
% Pro:
0
0
0
0
12
12
12
0
12
0
12
0
0
12
0
% P
% Gln:
12
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
12
0
12
56
0
0
0
0
0
0
0
12
23
0
0
% R
% Ser:
12
0
0
0
0
56
56
0
0
0
0
0
0
56
56
% S
% Thr:
0
0
12
0
0
0
12
0
56
0
12
56
0
12
0
% T
% Val:
0
0
0
0
0
12
0
0
12
12
0
0
0
0
0
% V
% Trp:
0
0
0
0
12
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
12
0
0
0
12
56
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _